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MCP Server

MCP-Slicer

Connects 3D Slicer with AI assistants through the Model Context Protocol, enabling medical image processing and scene manipulation using natural language.

19
GitHub Stars
11/22/2025
Last Updated
MCP Server Configuration
1{
2 "name": "slicer",
3 "command": "uvx",
4 "args": [
5 "mcp-slicer"
6 ]
7}
JSON7 lines
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README Documentation

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MCP-Slicer - 3D Slicer Model Context Protocol Integration

English | 简体中文

MCP-Slicer connects 3D Slicer with model clients like Claude Desktop or Cline through the Model Context Protocol (MCP), enabling direct interaction and control of 3D Slicer. This integration allows for medical image processing, scene creation, and manipulation using natural language.

Features

  1. list_nodes: List and filter Slicer MRML nodes and view their properties

  2. execute_python_code: Execute Python code in the Slicer environment

  3. capture_screenshot: Capture real-time screenshots of Slicer views

    • Full application window (including module panels)
    • Individual slice views (Red/Yellow/Green)
    • 3D rendering view
    • Enables complete REACT loop with visual feedback

Installation

Prerequisites

  • 3D Slicer 5.8 or newer
  • Python 3.13 or newer
  • uv package manager

If you're on Mac, please install uv as

brew install uv

On Windows

powershell -c "irm https://astral.sh/uv/install.ps1 | iex"

and then

set Path=C:\Users\nntra\.local\bin;%Path%

Otherwise installation instructions are on their website: Install uv

⚠️ Please install UV first

Claude for Desktop Integration

Go to Claude > Settings > Developer > Edit Config > claude_desktop_config.json to include the following:

{
  "mcpServers": {
    "slicer": {
      "command": "uvx",
      "args": ["mcp-slicer"]
    }
  }
}

Cline Intergration

{
  "mcpServers": {
    "slicer": {
      "command": "uvx",
      "args": ["mcp-slicer"]
    }
  }
}

Usage

Check Claude Settings

Image Make sure you see the corresponding slicer tools added to the Claude Desktop App Image Image

Open Slicer Web Server

  1. Open the Slicer Web Server module,
  2. ensure the required interfaces are checked,
  3. then start the server
Image

Examples

- list_nodes

What Markups nodes are in the Slicer scene now, list their names, what is their length if it is a line, and what is its angle if it is an angle

Image

- execute python code

Draw a translucent green cube of 8 cm in the Slicer scene, mark its vertices, and then draw a red sphere inscribed in it.

example_code_execute_en

- capture_screenshot

Capture the current state of Slicer to provide visual feedback to AI

Usage examples:

  • capture_screenshot() - Capture full application window
  • capture_screenshot(view_type="slice", view_name="red") - Capture Red slice view
  • capture_screenshot(view_type="3d", camera_axis="A") - Capture 3D view from anterior

This enables a complete REACT loop where AI can:

  1. Reason about what to do
  2. Act using execute_python_code
  3. Observe the result using capture_screenshot

Technical Details

Utilizes existing Slicer Web Server interfaces. For technical details, please see Slicer web server user guide

Limitations & Security Considerations

  • The execute_python_code tool allows running arbitrary Python code in 3D Slicer, which is powerful but potentially dangerous.

    ⚠️ Not recommended for production use.

  • Complex operations may need to be broken down into smaller steps.

Contributing

Contributions are welcome! Feel free to submit Pull Requests.

Disclaimer

This is a third-party integration project, not developed by the 3D Slicer team.

Quick Install

Quick Actions

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Key Features

Model Context Protocol
Secure Communication
Real-time Updates
Open Source

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