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MCP Server

bioRxiv-MCP-Server

šŸ” Enable AI assistants to search and access bioRxiv papers through a simple MCP interface. The bioRxiv MCP Server provides a bridge between AI assistants and bioRxiv's preprint repository through the Model Context Protocol (MCP). It allows AI models to search for biology preprints and access their

22
GitHub Stars
3/10/2026
Last Updated
MCP Server Configuration
1{
2 "name": "biorxiv",
3 "command": "python",
4 "args": [
5 "-m",
6 "biorxiv-mcp-server"
7 ]
8}
JSON8 lines
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README Documentation

bioRxiv MCP Server

šŸ” Enable AI assistants to search and access bioRxiv papers through a simple MCP interface.

The bioRxiv MCP Server provides a bridge between AI assistants and bioRxiv's preprint repository through the Model Context Protocol (MCP). It allows AI models to search for biology preprints and access their metadata in a programmatic way.

šŸ¤ Contribute • šŸ“ Report Bug

✨ Core Features

  • šŸ”Ž Paper Search: Query bioRxiv papers with keywords or advanced search āœ…
  • šŸš€ Efficient Retrieval: Fast access to paper metadata āœ…
  • šŸ“Š Metadata Access: Retrieve detailed metadata for specific papers āœ…
  • šŸ“Š Research Support: Facilitate biological sciences research and analysis āœ…
  • šŸ“„ Paper Access: Download and read paper content šŸ“
  • šŸ“‹ Paper Listing: View all downloaded papers šŸ“
  • šŸ—ƒļø Local Storage: Papers are saved locally for faster access šŸ“
  • šŸ“ Research Prompts: A set of specialized prompts for paper analysis šŸ“

šŸš€ Quick Start

Prerequisites

  • Python 3.10+
  • FastMCP library

Installation

  1. Clone the repository:

    git clone https://github.com/JackKuo666/bioRxiv-MCP-Server.git
    cd bioRxiv-MCP-Server
    
  2. Install the required dependencies:

    pip install -r requirements.txt
    

Installing via Smithery

To install bioRxiv Server for Claude Desktop automatically via Smithery:

claude
npx -y @smithery/cli@latest install @JackKuo666/biorxiv-mcp-server --client claude --config "{}"
Cursor

Paste the following into Settings → Cursor Settings → MCP → Add new server:

  • Mac/Linux
npx -y @smithery/cli@latest run @JackKuo666/biorxiv-mcp-server --client cursor --config "{}" 
Windsurf
npx -y @smithery/cli@latest install @JackKuo666/biorxiv-mcp-server --client windsurf --config "{}"
CLine
npx -y @smithery/cli@latest install @JackKuo666/biorxiv-mcp-server --client cline --config "{}"
Usage with Claude Desktop

Add this configuration to your claude_desktop_config.json:

(Mac OS)

{
  "mcpServers": {
    "biorxiv": {
      "command": "python",
      "args": ["-m", "biorxiv-mcp-server"]
      }
  }
}

(Windows version):

{
  "mcpServers": {
    "biorxiv": {
      "command": "C:\\Users\\YOUR_USERNAME\\AppData\\Local\\Programs\\Python\\Python311\\python.exe",
      "args": [
        "-m",
        "biorxiv-mcp-server"
      ]
    }
  }
}

Using with Cline

{
  "mcpServers": {
    "biorxiv": {
      "command": "bash",
      "args": [
        "-c",
        "source /home/YOUR/PATH/mcp-server-bioRxiv/.venv/bin/activate && python /home/YOUR/PATH/mcp-server-bioRxiv/biorxiv_server.py"
      ],
      "env": {},
      "disabled": false,
      "autoApprove": []
    }
  }
}

šŸ“Š Usage

Start the MCP server:

python biorxiv_server.py

šŸ›  MCP Tools

The bioRxiv MCP Server provides the following tools:

  1. search_biorxiv_key_words: Search for articles on bioRxiv using keywords.
  2. search_biorxiv_advanced: Perform an advanced search for articles on bioRxiv with multiple parameters.
  3. get_biorxiv_metadata: Fetch metadata for a bioRxiv article using its DOI.

Searching Papers

You can ask the AI assistant to search for papers using queries like:

Can you search bioRxiv for recent papers about genomics?

Getting Paper Details

Once you have a DOI, you can ask for more details:

Can you show me the metadata for the paper with DOI 10.1101/123456?

šŸ“ Project Structure

  • biorxiv_server.py: The main MCP server implementation using FastMCP
  • biorxiv_web_search.py: Contains the web scraping logic for searching bioRxiv

šŸ”§ Dependencies

  • Python 3.10+
  • FastMCP
  • asyncio
  • logging

šŸ¤ Contributing

Contributions are welcome! Please feel free to submit a Pull Request.

šŸ“„ License

This project is licensed under the MIT License.

āš ļø Disclaimer

This tool is for research purposes only. Please respect bioRxiv's terms of service and use this tool responsibly.

Quick Install

Quick Actions

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Key Features

Model Context Protocol
Secure Communication
Real-time Updates
Open Source

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