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This dataset comprises various MRI images for automated multiple‑sclerosis (MS) diagnosis. It includes: - **SCLEROSIS**: 109 images. - **ISBI 2015** challenge: 21 images for longitudinal MS lesion segmentation. - **Ljubljana**: 30 training images. - **MICCAI 2008**: 51 images for the MS lesion segmentation challenge. - **MICCAI 2016**: 15 training images. - **HEALTHY**: 21 healthy subject images. - **KIRBY**: 42 images for multimodal MRI reproducibility. - **OASIS‑3**: forthcoming. The dataset provides detailed demographic information for several subsets (age, sex, MS subtype, etc.) and includes download instructions and preprocessing protocols such as rigid registration, MNI alignment, anisotropic filtering, skull stripping, and bias field correction.
