PREVENT-AD open Dataset
The PREVENT‑AD (Pre‑symptomatic Evaluation of Alzheimer’s Disease) cohort consists of cognitively healthy participants aged 55 + who are at risk of developing Alzheimer’s disease (AD) because a parent and/or sibling is affected. Since 2011, these high‑risk participants have been followed in a naturalistic study of the pre‑symptomatic phase of AD using multimodal measurements of various disease markers. A clinical trial testing a drug preventive agent has also been conducted. The PREVENT‑AD research team is now publicly releasing the data to support the growing community demand for AD pathogenesis research.
Dataset description and usage context
PREVENT‑AD Open Dataset Overview
Dataset Overview
PREVENT‑AD (Pre‑symptomatic Evaluation of Alzheimer’s Disease) cohort consists of cognitively healthy participants older than 55 years who are at risk of developing Alzheimer’s disease (AD) because a parent and/or sibling is affected. Since 2011, these “high‑risk” participants have been studied naturally with multimodal measurements of various disease markers to investigate the pre‑symptomatic stage of AD. In addition, a clinical trial testing a drug preventive agent has been performed.
Data Organization
The dataset is organized using a candidate_id/visit_label hierarchy:
preventad-open
|__DATS.json
|__candidate_id
|__candidate.json
|__visit_label
|__visit.json
|__handedness.json
|__images
|__image_1.mnc
|__image_2.mnc
|__image_3.mnc
DATS.json: JSON file describing the dataset contents.candidate.json: Basic demographic information of the participant.visit.json: Visit‑level information.handedness.json: When available, contains results from the Edinburgh Handedness Inventory.- Images are provided in MINC format.
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